How much booze did the cast drink in this? Did Jame Best think before he signed on for this stinker?

The professor delivers the most garbled lines ever and it's great when Joel and the bots try to figure out what he's saying.

Griswold says the most peculiar line, something about Dixieland jazz. He made good Shrew chew.

This is the one where the 'shrews' are actually German shepherds in ratty monster masks, right?

I think they were dogs draped with huge mop bottoms...the scene where the actors are under their "anti shrew barrles" has got to be the silliest part in the film.

Well, that and Griswold screaming in fear at the top of a tree....

Narrator: “The wildest and most vicious of all animals ...”
Joel: “... are in Vegas.”

Professor: “Do you know there’s a hurricane coming?”
Crow: “No, but if you hum a few bars ...”

(Radford comes in holding something carefully in both hands)
Joel (as Professor): “He’s a brilliant man, but he saves his phlegm.”

Thorne: “How big do they get?”
(Dramatic music)
Tom (as Professor): “How big does that music make it sound?”

Ann: “There are two or three hundred giant shrews out there.”
Joel: “Not counting the dogs, right?”
Ann: “Monsters weighing between fifty and a hundred pounds.”
Crow: “How did she weigh ‘em?!”

“I don’t know everything. I don’t even know how fish work.”

Professor: “Miles of open water in any direction.”
Joel: “Miles of Keefe in every direction.”

Jerry (drunkenly): “You know what I’ve been thinking about, Mario?”
Tom (as a drunk Jerry): “Socks. I don’t know why.”
Jerry: “Ann ... and that captain ... You, and me.”
Crow (as Mario): “We will need a bigger room, then.”

“He chewed up the slippers! Bad shrew!”

“This is just like Aliens ... except without the underwear.”

(A glimpse of a giant shrew in the basement)
Joel: “There’s a Muppet behind the stairs! Honey, I think we got puppets down here!”
Crow: “Hand puppets?”
Joel: “Yeah! They’re under the stairs, so I don’t think they’re marionettes.”

(The shrew bites Mario, who shoots it)
Tom (as Mario): “Bad puppet!”
Joel (as Mario, in an Inspector Clouseau accent): “I thought you said your derg does not bite.”
Crow (in French accent): “That is not my dog.”

(Mario dies)
Thorne: “What could have killed him?”
Tom: “Oh, I dunno – maybe that shrew?!”

Ann: “[I’d] rather [be] dull and alive, then.”
Thorne: “I’ll take that dull, alive woman every time.”
Tom: “I guess the other way would be kind of sick, wouldn’t it?”

Jerry: “Say, Thorne.”
Joel and the Bots (simultaneously): “Thorne.”

Tom (singing): “How deadly is that doggie in the window?”

(Ann and Thorne look over the fence at the dead shrew)
Tom (as Thorne): “Oh, wait, here’s a trick I taught him: Stay. Rot. Good boy!”

Jerry: “Sure, I’ll go.”
Crow (as Jerry): “If I die, it’ll be a boon to the movie.”

(Thorne tries to attract attention from the boat by whistling through two fingers)
“Don’t do that! They’re dogs!”

(Thorne and Jerry find Rocko’s remains)
Crow: “Well, either he’s dead or they found Amelia Earhart’s stuff.”
Thorne: “They don’t leave much, do they?”
Tom: “Oh, I don’t know – that’s a shoe, a gun, a belt, a shirt. Lots of stuff!”

Jerry: “They’re coming!”
Joel: “To take me away!”
Tom: “Ha ha!”

“Don’t run! Dogs can sense fear!”

(Radford gets bitten by a shrew. He sits down and starts to type)
Crow (narrating): “The ... end.”

“I think this movie just broke the goofy-meter.”

(The survivors start to swim out into the ocean)
“”Oh no! Piranha! Sharks!”

I've seen this one too. Just don't take it too seriously, and you'll be fine.