Scorpion- Can opener. Lithium
Doc Ock- Rip those arms off. Valium
Rhino- Can opener. Prozac.
Venom- thearpy on why spider-man is not the sorce of his problems. Asprin
Hobgoblin- Just kill him
Vulture- Talk to dick clark.
Matt, the word is "therapy".
Lizard-Just throw him in with the alligators or crocodiles in some zoo and keep him there. Yeah, yeah,I know it's reminiscient of his first appearance but so what? Oh, and let him eat Hobgoblin's rotting corpse, too, but tell him it's really Spider-man's. That should satisfy him.